Applying these to your weapon will make your arrows far more powerful, to the extent that you’ll be tearing through ancient dragons like it’s nobody’s business. Once you’ve taken care of all of this, you’ll need to use Alchemy to craft devastating poisons. On top of this, you’ll need a bow enchanted with elemental damage and soul trap - to keep it topped up - as well as the best arrows money can buy.
The goal is to kit yourself out in light armour with Sneak enchantments.